Matt Hancock's dramatically raising hopes of a Covid-19 vaccine within months. The Health Secretary says it's “looking up” that a drug being developed by experts at the University of Oxford and pharmaceutical giant AstraZeneca would be granted approval for use soon after trials in several countries, including the UK, US and Brazil. But the Evening Standard's deputy political editor Nicholas Cecil says we've yet hear confirmation from the medical community, and with coronavirus cases rising again the government needs to deliver on its promises to retain public confidence. 

And, bust up or brinkmanship? Our associate editor Julian Glover looks at what's going on with Brexit. The Prime Minister's vowing he "won't back down" as alarms sound following reports the government's planning to overwrite parts of the Withdrawal Agreement. It could lead to trade talks collapsing in mid-October, and a "no deal" scenario returning to discussions. Could the UK really "prosper mightily" as the Prime Minister claims?

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