Nearly two years after COVID-19 was identified, and a year after mass vaccination began, Britain could be on the brink of another lockdown. How did we get here? How serious is Omicron? Is it intrinsically milder, will our antibodies keep it mild, will it cause less severe illness, hospitalisation and death - and what does the evidence from abroad tell us?

We're joined by the Financial Times' brilliant John Burn-Murdoch - whose data and analysis has been a lifeline through the pandemic - to guide us through the current crisis.

Plus: Director of CLASS Ellie Mae O'Hagan talks us through the politics of the current moment - will a pandemic-weary public really stand for another lockdown, what does the Tory crisis mean for public health - and what comes next?

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