#114 Nutrigenomics and Medicine with Dr Yael Joffe

Dr Yael Joffe is a registered dietitian in South Africa who specialises in nutrigenomics and Functional Nutrition. She has been involved in several research collaborations with key academic partners from around the world, and is often to be found at the front lines raising awareness about nutrigenomic and Functional Nutrition applications for health practitioners and the public alike.

In addition to her research and development work for DNAlysis Biotechnology, Yael is also a faculty member of the Institute for Functional Medicine and is involved in advancing the understanding and integration of Functional Nutrition in South Africa. Yael obtained her PhD from the University of Cape Town, exploring the genetics and nutrition of obesity in South African women. 

Today we talk about:

  • 07.00 What a gene is and how ‘spelling mistakes’ occur
  • 15.55 Monogenic vs Polygenic genes
  • 18.00 The process of determining which SNPs (spelling mistakes) to include in a genomic profile
  • 18.50 Detoxification SNPs
  • 22.00 The change in gene technology over 20 years
  • 27.00 Appetite and weight regulation
  • 32.00 Detoxification, Sulforaphane and NRF-2
  • 42.00 Differences between ethnicities and the lack of genomic research in non-caucasian
  • 46.00 Alzeihmers risk and the importance of APO-E4
  • 49.00 COVID response

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