Using “ONEST” algorithm to improve reproducibility of PD-L1 assessment by pathologists

A conversation with David Rimm, the author of a recent study on Triple negative breast cancer, on using a novel statistical algorithm (ONEST) to improve reproducibility of PD-L1 assessment by pathologists.


Study by Reisenbichler et al, Prospective multi-institutional evaluation of pathologist assessment of PD-L1 assays for patient selection in triple negative breast cancer. Modern Pathology, 2020. https://www.nature.com/articles/s41379-020-0544-x


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